c. diff
Issue Background

Antibiotic Stewardship

According to the Centers for Disease Control and Prevention, upt to 50% of all antibiotics prescribed in U.S. acute care hospitals are either unnecessary or inappropriate.

Since their introduction into medicine in 1941, antibiotics have saved millions of lives and transformed modern medicine. As a result, bacterial infections have become easily treatable, and the horizons for surgeries, transplants, and more complicated life-saving procedures have expanded. But increasing antibiotic resistance is leading to higher treatment costs, longer hospital stays, and unnecessary deaths.

The more we use antibiotics, the more we contribute to the pool of antibioticresistant microbes. The development of resistance is an inevitable byproduct of exposure to antibiotics. All antibiotic use, whether warranted or not, places selection pressure on bacteria, and some organisms that possess genetic mutations will survive antibiotic treatment. Over time, resistance threatens to return us to an era where simple bacterial infections will once again be deadly.